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From Chapter 1:
The form and make of the first pipe is a matter I do not propose to go into here; but in connexion with the first pipe smoked in this country Aubrey's interesting statements must be given. Writing in the time of Charles II, he said that he had heard his grandfather say that at first one pipe was handed from man to man round about the table. "They had first silver pipes; the ordinary sort made use of a walnut shell and a straw"—surely a very unsatisfactory pipe. Tobacco in those earliest days, he says, was sold for its weight in silver. "I have heard some of our old yeomen neighbours say that when they went to Malmesbury or Chippenham Market, they culled out their biggest shillings to lay in the scales against the tobacco."

From Chapter 5:
Among the many medicinal virtues attributed to tobacco was its supposed value as a preservative from contagion at times of plague. Hearne, the antiquary, writing early in 1721, said that he had been told that in the Great Plague of London of 1665 none of those who kept tobacconists' shops suffered from it, and this belief no doubt enhanced the medical reputation of the weed. I have also seen it stated that during the cholera epidemics of 1831, 1849, and 1866 not one London tobacconist died from that disease; but good authority for the statement seems to be lacking. Hutton, in his "History of Derby," says that when that town was visited by the plague in 1665, that at the "Headless-cross ... the market-people, having their mouths primed with tobacco as a preservative, brought their provisions.... It was observed, that this cruel affliction never attempted the premises of a tobacconist, a tanner or a shoemaker." Whatever ground there may have been for the belief in the prophylactic effect of smoking, there can be no doubt that in the seventeenth century it was firmly held. Howell in one of his "Familiar Letters" dated January 1, 1646, says that the smoke of tobacco is "one of the wholesomest sents that is against all contagious airs, for it overmasters all other smells, as King James they say found true, when being once a hunting, a showr of rain drave him into a Pigsty for shelter, wher he caus'd a pipe full to Be taken of purpose." But here Mr. Howell is certainly drawing the long-bow. One cannot imagine the author of the "Counterblaste" countenancing the use of tobacco under any circumstances.